UASt regulatory sequences drive expression of an inverted repeat.
Expression of Ac76EGD2737 under the control of Scer\GAL4P2.4.Pdf significantly reduces the response of the M pacemaker neurons in the brain to Pdf. This effect is no longer seen if expression is restricted to the adult stage by use of the temperature-sensitive Scer\GAL80ts.αTub84B allele.
Adults expressing Ac76EGD2737 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.