FlyBase Allele Report: Dmel\babo[unspecified]

General Information

Symbol

Dmel\babo^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0195710

Feature type

allele

Associated gene

Dmel\babo

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy

(Boulanger et al., 2011)

Phenotype Manifest In

embryonic/larval brain

(Zhu et al., 2008)

gamma Kenyon cell

(Boulanger et al., 2011)

Detailed Description

Statement

Reference

Mutations in babo block γ-neuron remodelling.

(Boulanger et al., 2011)

The brain lobes of mutant third instar larvae are 25-40% smaller than those of heterozygous controls.

(Zhu et al., 2008)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

babo^unspecified has abnormal neuroanatomy phenotype, non-enhanceable by Hr39^c739

(Boulanger et al., 2011)

Hr39^c739, babo^unspecified has abnormal neuroanatomy phenotype, non-enhanceable by ftz-f1^β.UAS.cBa/Scer\GAL4^Tab2-201Y

(Boulanger et al., 2011)

Suppressed by

Statement

Reference

babo^unspecified has abnormal neuroanatomy phenotype, suppressible | partially by Scer\GAL4^Tab2-201Y/EcR^B1.UAS

(Boulanger et al., 2011)

Hr39^c739, babo^unspecified has abnormal neuroanatomy phenotype, suppressible | partially by Scer\GAL4^Tab2-201Y/EcR^B1.UAS

(Boulanger et al., 2011)

NOT suppressed by

Statement

Reference

babo^unspecified has abnormal neuroanatomy phenotype, non-suppressible by Hr39^c739

(Boulanger et al., 2011)

Hr39^c739, babo^unspecified has abnormal neuroanatomy phenotype, non-suppressible by ftz-f1^β.UAS.cBa/Scer\GAL4^Tab2-201Y

(Boulanger et al., 2011)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

babo^unspecified has gamma Kenyon cell phenotype, non-enhanceable by Hr39^c739

(Boulanger et al., 2011)

Hr39^c739, babo^unspecified has gamma Kenyon cell phenotype, non-enhanceable by ftz-f1^β.UAS.cBa/Scer\GAL4^Tab2-201Y

(Boulanger et al., 2011)

Suppressed by

Statement

Reference

babo^unspecified has gamma Kenyon cell phenotype, suppressible | partially by Scer\GAL4^Tab2-201Y/EcR^B1.UAS

(Boulanger et al., 2011)

Hr39^c739, babo^unspecified has gamma Kenyon cell phenotype, suppressible | partially by Scer\GAL4^Tab2-201Y/EcR^B1.UAS

(Boulanger et al., 2011)

NOT suppressed by

Statement

Reference

babo^unspecified has gamma Kenyon cell phenotype, non-suppressible by Hr39^c739

(Boulanger et al., 2011)

Hr39^c739, babo^unspecified has gamma Kenyon cell phenotype, non-suppressible by ftz-f1^β.UAS.cBa/Scer\GAL4^Tab2-201Y

(Boulanger et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Restoration of EcR, through expression of EcR^B1.Scer\UAS in a babo^unspecified mutant background partially rescues the γ-neuron remodelling defects in these mutants.

A Hr39^c739 homozygous mutant background does not affect the mutant pruning phenotype seen in babo^unspecified mutant γ neurons.

Expression of ftz-f1^{β.Scer\UAS.cBa} in a babo^unspecified Hr39^c739 double mutant background, under the control of Scer\GAL4^Tab2-201Y does not affect the mutant pruning phenotype seen in these double mutant γ neurons.

Restoration of EcR, through expression of EcR^B1.Scer\UAS in a babo^unspecified Hr39^c739 double mutant background, under the control of Scer\GAL4^Tab2-201Y partially rescues the γ-neuron remodelling defects in these mutants.

(Boulanger et al., 2011)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

babo^k16912

(Dworkin and Gibson, 2006)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

babo^unspecified

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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