In olfactory preference assays for polyamines, Ir76bMB00216/Ir76bMB00216 flies show a significant decrease in their attraction to putrescine or cadaverine, as compared to wild type. Ir76bMB00216/Ir76bMB00216 females display a loss of aversion to oviposit on polyamine-rich substrate (plain, sugar-free 1% agarose supplemented with either putrescine or cadaverine) versus non-supplemented substrate, in contrast to wild type flies, instead showing no preference for either substrate.