FB2024_03 , released June 25, 2024
Allele: Scer\GAL4Or42b.PF
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General Information
Symbol
Scer\GAL4Or42b.PF
Species
S. cerevisiae
Name
Odorant receptor 42b promoter construct of Fishilevich
FlyBase ID
FBal0190493
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{Or42b-GAL4.F}
Also Known As
Or42b-Gal4
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Fishilevich and Vosshall, 2005, Fishilevich et al., 2005)
Progenitor genotype
Carried in construct
P{Or42b-GAL4.F}
Cytology
Description

A 8.039kb Or42b promoter controls expression of a GAL4 driver.

(Fishilevich and Vosshall, 2005)
Allele components
Component
Use(s)
Regulatory region(s)
Or42b
Or42b_FV12
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      larval stage
      larval olfactory receptor neuron Or42b
      (Masuda-Nakagawa et al., 2009)
      larval antennal lobe glomerulus 42b
      (Masuda-Nakagawa et al., 2009)
      first instar larval stage -- third instar larval stage
      larval olfactory receptor neuron Or42b
      (Eschbach et al., 2021)
      adult stage
      adult olfactory receptor neuron Or42b
      (Fishilevich and Vosshall, 2005)
      antennal lobe glomerulus DM1
      (Fishilevich and Vosshall, 2005)
      antennal basiconic sensillum ab1
      (Larter et al., 2016)
      Additional Information
      Statement
      Reference

      Drives expression in adult and larval olfactory receptor neuron Or42b; antennal basiconic sensillum ab1; larval antennal lobe glomerulus 42b, and adult antennal lobe glomerulus ab1.

      (FlyBase Curators, 2017)
       
      Marker for
      larval olfactory receptor neuron Or42b
      (Eschbach et al., 2021)
      Reflects expression of
      Or42b
      (Eschbach et al., 2021, Larter et al., 2016, Masuda-Nakagawa et al., 2009, Fishilevich and Vosshall, 2005)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Inhibition (using Ctet\tetXTNT-LC.UAS) of Scer\GAL4Or42b.PF cells in flying adults does not substantially affect odor stream avoidance and attraction, compared to controls.

      (Badel et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      NOT Enhanced by
      NOT suppressed by
      Enhancer of
      Suppressor of
      Statement
      Reference

      Scer\GAL4Or42b.PF/Hsap\TMEM63BUAS.cLa is a suppressor of abnormal behavior | adult stage phenotype of Tmem63KO

      (Li et al., 2022)
      NOT Suppressor of
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Scer\GAL4Or42b.PF
      Name Synonyms
      Odorant receptor 42b promoter construct of Fishilevich
      (Fishilevich and Vosshall, 2005, Fishilevich et al., 2005)
      Secondary FlyBase IDs
        References (25)