FB2024_03 , released June 25, 2024
Allele: Bper\ptxAUAS.cKa
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General Information
Symbol
Bper\ptxAUAS.cKa
Species
B. pertussis
Name
Saccharomyces cerevisiae UAS construct a of Katanaev
FlyBase ID
FBal0187985
Feature type
allele
Associated gene
Bper\ptxA
Associated Insertion(s)
Carried in Construct
P{UAS(-FRT)ptxA.K}
Also Known As
UAS-Ptx
Transgenic product class
wild_type
(Katanaev et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Katanaev et al., 2005)
Mutagen
FLPase
(Katanaev et al., 2005)
Progenitor genotype
Bper\ptxAFRT.UAS
(Katanaev et al., 2005)
Carried in construct
P{UAS(-FRT)ptxA.K}
Cytology
Description

The FRT cassette has been excised, juxtaposing the UAS regulatory sequences and Bper\ptxA coding region.

(Katanaev et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Bper\ptxA
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Bper\ptxAScer\UAS.cKa under the control of Scer\GAL4CCAP.PP reduces the duration of pupal pre-ecdysis behavior stage, while expression under two copies of Scer\GAL4Lk.PM has no significant effect on the stage length.

      (Kim et al., 2015)

      Expression of Bper\ptxAScer\UAS.cKa under the contro of Scer\GAL4Orco.PU leads to behavioural deficits. The percentage of flies choosing a vinegar trap (an attractive odour) over a neutral odour is lower in these flies, compared to control.

      (Ignatious Raja et al., 2014)

      The L-type sensilla of flies expressing Bper\ptxAScer\UAS.cKa under the control of Scer\GAL4Gr5a.PUn show a significantly reduced spike rate in response to sucrose (over a range of concentrations extending from 20 to 500mM) compared to wild-type control sensilla.

      Flies expressing Bper\ptxAScer\UAS.cKa under the control of Scer\GAL4Gr5a.PUn are completely unable to to discriminate between 2mM and 5mM sucrose in a 2-choice preference assay.

      Flies expressing Bper\ptxAScer\UAS.cKa under the control of Scer\GAL4Gr66a.PD show a normal avoidance response to caffeine and to quinine in a 2-choice preference assay.

      (Bredendiek et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Bper\ptxAScer\UAS.cKa
      Bper\ptxAUAS.cKa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Katanaev
      (Katanaev et al., 2005)
      Secondary FlyBase IDs
        References (6)