FlyBase Allele Report: Dmel\Mrtf[ΔNΔC.H.UAS]

General Information

Symbol

Dmel\Mrtf^ΔNΔC.H.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0182632

Feature type

allele

Associated gene

Dmel\Mrtf

Associated Insertion(s)

Carried in Construct

P{UAS-Mrtf.ΔNΔC.H}

Key Links

Transgenic product class

inframe_deletion

(Han et al., 2004)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

inframe_deletion

(Han et al., 2004)

Mutagen

in vitro construct

(Han et al., 2004)

Progenitor genotype

Carried in construct

P{UAS-Mrtf.ΔNΔC.H}

Cytology

Description

UASt regulatory sequences drive expression of the SRF-binding domain of Mrtf.

(Han et al., 2004)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Mrtf

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^Bx-MS1096

(Han et al., 2004)

Phenotype Manifest In

dorsal tracheal branch primordium, with Scer\GAL4^btl.PS

(Han et al., 2004)

ganglionic tracheal branch primordium, with Scer\GAL4^btl.PS

(Han et al., 2004)

mesoderm, with Scer\GAL4^da.G32

(Han et al., 2004)

presumptive embryonic/larval tracheal system, with Scer\GAL4^da.G32

(Han et al., 2004)

wing, with Scer\GAL4^Bx-MS1096

(Han et al., 2004)

wing cell, with Scer\GAL4^Bx-MS1096

(Han et al., 2004)

Detailed Description

Statement

Reference

Expression of Mrtf^{ΔNΔC.H.Scer\UAS} under the control of Scer\GAL4^btl.PS results in defects in the tracheal system in embryos; the dorsal and ganglionic branches are often truncated or missing. Expression of Mrtf^{ΔNΔC.H.Scer\UAS} under the control of Scer\GAL4^da.G32 in embryos results in inhibition of branching in the tracheal system. Defects in mesoderm migration are also seen in these embryos. Expression of Mrtf^{ΔNΔC.H.Scer\UAS} under the control of Scer\GAL4^Bx-MS1096 results in a reduction of intervein tissue in the wing and often results in a failure of the two layers of the wing to fuse completely.

(Han et al., 2004)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Mrtf^{ΔNΔC.H.Scer\UAS}

Mrtf^ΔNΔC.H.UAS

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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