FB2024_03 , released June 25, 2024
Allele: Dmel\byGFP
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General Information
Symbol
Dmel\byGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0180606
Feature type
allele
Associated gene
Dmel\by
Associated Insertion(s)
Carried in Construct
P{by.GFP}
Also Known As
tensin-gfp
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Torgler et al., 2004)
wild_type
(Torgler et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Torgler et al., 2004)
wild_type
(Torgler et al., 2004)
Mutagen
in vitro construct
(Torgler et al., 2004)
Progenitor genotype
Carried in construct
P{by.GFP}
Cytology
Description

A 11,029 bp MluI genomic fragment, containing 5775 bp upstream and 3090 bp downstream of the by coding region. The by ORF is fused at its 3' end to GFP via the linker sequence GSSSSSS.

(Torgler et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
by
Encoded product / tool
by
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
3R:9,527,729..9,538,753 [-]
Linked to:
MluI-MluI restriction fragment
Comment:

Fully rescues the by phenotype.

(Torgler et al., 2004)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter or direct label
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 16 -- 17
      muscle attachment site
      (Torgler et al., 2004)
      tendon cell
      (Torgler et al., 2004)
      embryonic stage 17
      embryonic/larval digestive system
      (Torgler et al., 2004)
      embryonic/larval pharynx
      (Torgler et al., 2004)
      embryonic/larval proventriculus
      (Torgler et al., 2004)
      P-stage
      wing

      Comment: basal integrin-mediated junction

      (Torgler et al., 2004)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      by
      (Torgler et al., 2004)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      byGFP is a non-suppressor of abnormal locomotor behavior | dominant | adult stage phenotype of MhcS1

      (Pronovost et al., 2013)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The poor climbing ability of MhcS1 heterozygous adults is not suppressed if the flies are also carrying byT:Avic\GFP.

      (Pronovost et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      byGFP rescues by33c

      (Torgler et al., 2004)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      by+t11.T:Avic\GFP
      byGFP
      byT:Avic\GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (7)