Scer\GAL4elav-C155/cacUAS.cKa partially rescues cacHC129
Scer\GAL4elav-C155/cacUAS.cKa partially rescues cac20-3
Neural expression of cacScer\UAS.cKa under the regulation of Scer\GAL4elav-C155 rescues cacTS2 paralysis at 38oC. In addition, expression of cacScer\UAS.cKa under the regulation of Scer\GAL4elav-C155 rescues the reduction in synaptic current amplitude as seen in cacTS2 mutants. The embryonic lethal phenotype of cac20-3 and cacHC129 mutants is rescued by cacScer\UAS.cKa under the regulation of Scer\GAL4elav-C155, along with general motor behaviour, activity and fertility. However, rescued flies are flightless and do not beat their wings under usual flight conditions.