FB2024_03 , released June 25, 2024
Allele: Dmel\simj7
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General Information
Symbol
Dmel\simj7
Species
D. melanogaster
Name
FlyBase ID
FBal0177959
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    simj7/simj16 animals survive to the late pupal stage. The pupae appear almost wild-type, but do display a variety of phenotypes, including legs that are bent back, a split notum and folded wings. Some mutants show necrosis near the head region, while others lacks pigmentation and bristles in the abdominal region. Some simjS/simj7 pupae show accumulation of white fluid (possibly due to incomplete histolysis of the fat bodies) which causes the pharate adult to stick to the pupal case.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Enhancer of
    Statement
    Reference

    simj7/simj[+] is an enhancer of visible phenotype of wgts.sev

    Phenotype Manifest In
    Enhancer of
    Statement
    Reference

    simj7/simj[+] is an enhancer of interommatidial bristle phenotype of wgts.sev

    Additional Comments
    Genetic Interactions
    Statement
    Reference

    The reduction in bristles in the eye seen in wgts.sev flies at 17.6oC is enhanced if they are also carrying simj7/+.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Fails to complement
    Partially rescued by
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer

    Selected as: a dominant modifier of the eye bristle phenotype of wgts.sev.

    Comments
    Comments

    Order of alleles (from weak to strong) is: simj16, simj7, simjL, simjS, simjH, simjJ = simj10 = simjA = Df(3L)lxd6.

    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    simj7
    Name Synonyms
    Secondary FlyBase IDs
      References (1)