FlyBase Allele Report: Dmel\simj[16]

General Information

Symbol

Dmel\simj¹⁶

Species

D. melanogaster

Name

FlyBase ID

FBal0177960

Feature type

allele

Associated gene

Dmel\simj

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Kon et al., 2005)

Progenitor genotype

simj^j4A5

(Kon et al., 2005)

Cytology

Description

Imprecise excision of the insertion in simj^j4A5.

(Kon et al., 2005)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of pupal stage (with simj⁷)

(Kon et al., 2005)

lethal - all die before end of pupal stage (with simj^L)

(Kon et al., 2005)

some die during pupal stage (with simj⁷)

(Kon et al., 2005)

some die during pupal stage (with simj^L)

(Kon et al., 2005)

Phenotype Manifest In

leg | P-stage (with simj⁷)

(Kon et al., 2005)

mesothoracic tergum | P-stage (with simj⁷)

(Kon et al., 2005)

metathoracic leg | P-stage (with simj^L)

(Kon et al., 2005)

pupal abdomen (with simj⁷)

(Kon et al., 2005)

wing | P-stage (with simj⁷)

(Kon et al., 2005)

Detailed Description

Statement

Reference

simj^L/simj¹⁶ animals survive to the late pupal stage. The pupae appear almost wild-type, but do display a variety of phenotypes, including short third legs. simj⁷/simj¹⁶ animals survive to the late pupal stage. The pupae appear almost wild-type, but do display a variety of phenotypes, including legs that are bent back, a split notum and folded wings. Some mutants show necrosis near the head region, while others lacks pigmentation and bristles in the abdominal region. Homozygous clones in the imaginal disc appear to be roughly equal in size to their twin spots, indicating that simj is not essential for cell viability or cell growth.

(Kon et al., 2005)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Order of alleles (from weak to strong) is: simj¹⁶, simj⁷, simj^L, simj^S, simj^H, simj^J = simj¹⁰ = simj^A = Df(3L)lxd6.

(Kon et al., 2005)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

p66¹⁶

(Kon et al., 2005)

simj¹⁶

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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