FB2024_03 , released June 25, 2024
Allele: Dmel\β4GalNAcTBGT
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General Information
Symbol
Dmel\β4GalNAcTBGT
Species
D. melanogaster
Name
FlyBase ID
FBal0176435
Feature type
allele
Associated gene
Dmel\β4GalNAcTB
Associated Insertion(s)
TI{TI}β4GalNAcTBGT
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
recombination
(Haines and Irvine, 2005)
FLPase
(Haines and Irvine, 2005)
ends-out gene targeting
(Haines and Irvine, 2005)
Progenitor genotype
Associated Insertion(s)
TI{TI}β4GalNAcTBGT
Cytology
Description

200bp deletion in the middle of the β4GalNAcTB transcription unit. A w+mW.hs marker has been inserted in place of the deleted sequence.

(Haines and Irvine, 2005)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous adults are recovered and they appear morphologically normal and do not have behavioural phenotypes.

      (Haines and Irvine, 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      β4GalNAcTBGT β4GalNAcTA4.1 double mutants are viable, fertile and morphologically normal. The double mutant flies show locomotor defects (reduced climbing ability and bang sensitivity) similar to those seen in β4GalNAcTA4.1 single mutants.

      (Haines and Irvine, 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      β4GalNAcTBGT
      Name Synonyms
      Secondary FlyBase IDs
        References (1)