Flies expressing edlScer\UAS.T:Hsap\MYC under the control of Scer\GAL4tsh-md621 have notum defects and small, malformed wings.
Flies expressing edlScer\UAS.T:Hsap\MYC under the control of Scer\GAL4hs.2sev have wild-type eyes. Expression of edlScer\UAS.T:Hsap\MYC under the control of Scer\GAL4GMR.PF results in gross disorganisation of the external morphology of the adult eye. Eye imaginal discs show increased cell death posterior to the morphogenetic furrow in third instar larvae expressing edlScer\UAS.T:Hsap\MYC under the control of Scer\GAL4GMR.PF.
Scer\GAL4GMR.PF, edlUAS.Tag:MYC has increased cell death phenotype, suppressible by pntP2.UAS.Tag:FLAG/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, edlUAS.Tag:MYC has visible phenotype, suppressible by pntP2.UAS.Tag:FLAG/Scer\GAL4GMR.PF
edlUAS.Tag:MYC/Scer\GAL4hs.2sev is an enhancer of visible phenotype of aopACT.sev
Scer\GAL4GMR.PF, edlUAS.Tag:MYC has eye disc phenotype, suppressible by pntP2.UAS.Tag:FLAG/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, edlUAS.Tag:MYC has eye phenotype, suppressible by pntP2.UAS.Tag:FLAG/Scer\GAL4GMR.PF
edlUAS.Tag:MYC/Scer\GAL4hs.2sev is an enhancer of eye phenotype of aopACT.sev
The rough eye phenotype caused by aopACT.sev is enhanced by expression of edlScer\UAS.T:Hsap\MYC under the control of Scer\GAL4hs.2sev. Co-expression of pntP2.Scer\UAS.T:Zzzz\FLAG completely rescues the severe rough eye phenotype caused by expression of edlScer\UAS.T:Hsap\MYC under the control of Scer\GAL4GMR.PF, restores the normal recruitment of photoreceptors and cone cells and reduces cell death to wild-type levels.