FB2024_03 , released June 25, 2024
Allele: Dmel\sizP2.UAS
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General Information
Symbol
Dmel\sizP2.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0175511
Feature type
allele
Associated gene
Dmel\siz
Associated Insertion(s)
Carried in Construct
P{UAS-siz.P2}
Key Links
Transgenic product class
cDNA
(Onel et al., 2004)
wild_type
(Onel et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Onel et al., 2004)
wild_type
(Onel et al., 2004)
Mutagen
in vitro construct
(Onel et al., 2004)
Progenitor genotype
Carried in construct
P{UAS-siz.P2}
Cytology
Description

Expression of sizP2 isoform (LP01489), is under the control of UAS sequences.

(Onel et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
siz
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of sizP2.Scer\UAS under the control of Scer\GAL4GMR.PF has little effect on rhabdomere development of accumulation of membranes within the cell body of the photoreceptor cells.

      (Raghu et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of sizP2.Scer\UAS does not enhance the photoreceptor cell phenotypes caused by expression of PldScer\UAS.cRa under the control of Scer\GAL4GMR.PF.

      (Raghu et al., 2009)

      Mild fusion of commissures occurs in sli550/+ embryos that also carry sizP2.Scer\UAS; Scer\GAL4sim.PS. This phenotype does not occur in sizP2.Scer\UAS; Scer\GAL4sim.PS embryos or sli550/+ embryos.

      (Onel et al., 2004)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      sizP2.UAS/Scer\GAL4sli.PS rescues sizU112

      (Onel et al., 2004)

      sizP2.UAS/Scer\GAL4sim.PS rescues sizU112

      (Onel et al., 2004)
      Comments

      Reduction of ventral nerve cord commissures in sizU112 homozygotes is rescued by sizP2.Scer\UAS with Scer\GAL4sim.PS or Scer\GAL4sli.PS.

      (Onel et al., 2004)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      sizP2.Scer\UAS
      sizP2.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)