FB2024_04 , released June 25, 2024
Allele: Dmel\kisEY12846
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General Information
Symbol
Dmel\kisEY12846
Species
D. melanogaster
Name
FlyBase ID
FBal0159122
Feature type
allele
Associated gene
Dmel\kis
Associated Insertion(s)
P{EPgy2}kisEY12846
Carried in Construct
Also Known As
EY12846
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{EPgy2}kisEY12846
Cytology
Description

Insertion at nucleotide +1430 relative to the transcription start site.

(Schneiderman et al., 2009)
Allele components
Component
Use(s)
Inserted element
P{EPgy2}
Regulatory region(s)
UASp
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of kisEY12846 under the control of Scer\GAL4GMR.PF increases the eye pigmentation in Dp(?;2)bwD/bw[+] animals.

      (Schneiderman et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      kis[+]/kisEY12846 is a suppressor of wing vein | adult stage phenotype of Marcal1UAS.cBa, Scer\GAL4Tub.PU

      (Morimoto et al., 2016)

      kis[+]/kisEY12846 is a suppressor of wing vein | adult stage phenotype of Hsap\SMARCAL1UAS.cBa, Scer\GAL4Bx-MS1096

      (Morimoto et al., 2016)

      kisEY12846/Scer\GAL4GMR.PF is a suppressor of eye phenotype of bwD

      (Schneiderman et al., 2010)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The formation of ectopic wing veins observed in adult flies expressing Marcal1Scer\UAS.cBa under the control of Scer\GAL4tub.PU is ameliorated by combination with a single copy of kisEY12846.

      (Morimoto et al., 2016)

      Mis-expression of kisEY12846 driven by Scer\GAL4GMR.PF results in increased eye pigmentation in bwD/+ heterozygotes compared with that in the parental bwD/+ line.

      (Schneiderman et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference

      The formation of ectopic wing veins observed in adult flies expressing Hsap\SMARCAL1Scer\UAS.cBa under the control of Scer\GAL4Bx-MS1096 is ameliorated by combination with a single copy of kisEY12846.

      (Morimoto et al., 2016)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      kisEY12846
      (Verma and Cohen, 2015)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)