FB2024_03 , released June 25, 2024
Allele: Dmel\Pgant4f02186
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General Information
Symbol
Dmel\Pgant4f02186
Species
D. melanogaster
Name
FlyBase ID
FBal0158822
Feature type
allele
Associated gene
Dmel\Pgant4
Associated Insertion(s)
PBac{WH}Pgant4f02186
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
piggyBac activity
(Bloomington Drosophila Stock Center, 2004.11.6)
Progenitor genotype
Associated Insertion(s)
PBac{WH}Pgant4f02186
Cytology
Description
Allele components
Component
Use(s)
Inserted element
PBac{WH}
Regulatory region(s)
UAS
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The secretory cells (PR cells) of the proventriculus of pgant4f02186/Df(2L)tim-02 larvae show disrupted morphology and secretion, are enlarged, and display loss of apical secretory components and secretory granules, compared to wild type.

      (Zhang et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Df(2L)tim-02/Pgant4f02186 is rescued by Pgant4UAS.cZa

      (Zhang et al., 2014)

      Pgant4f02186 is rescued by Pgant4UAS.cZa/Scer\GAL4unspecified

      (Zhang et al., 2014)
      Not rescued by

      Df(2L)tim-02/Pgant4f02186 is not rescued by Pgant4m2.UAS

      (Zhang et al., 2014)

      Pgant4f02186 is not rescued by Scer\GAL4unspecified/Pgant4m2.UAS

      (Zhang et al., 2014)
      Comments

      Expression of pgant4Scer\UAS.cZa, but not pgant4m4.Scer\UAS, rescues the aberrant secretory apparatus structure and defective secretion seen in the PR cells of the proventriculus of pgant4 mutant larvae.

      (Zhang et al., 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Pgant4f02186
      pgant4f02186
      (Zhang et al., 2017, Zhang et al., 2014)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)