FlyBase Allele Report: Dmel\Acf[EY08629]

General Information

Symbol

Dmel\Acf^EY08629

Species

D. melanogaster

Name

FlyBase ID

FBal0157500

Feature type

allele

Associated gene

Dmel\Acf

Associated Insertion(s)

P{EPgy2}Acf^EY08629

Carried in Construct

Also Known As

EY08629

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{EPgy2}Acf^EY08629

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{EPgy2}

misexpression element

Regulatory region(s)

UASp

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:31,794,042..31,794,042 [+]

(Schneiderman et al., 2010, Fyodorov et al., 2004)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Acf^EY08629, Scer\GAL4^GMR.PF, bw^D has abnormal eye color | dominant phenotype, non-enhanceable by Hsap\CDKN1A^GMR.PH

(Schneiderman et al., 2010)

NOT suppressed by

Statement

Reference

Acf^EY08629, Scer\GAL4^GMR.PF, bw^D has abnormal eye color | dominant phenotype, non-suppressible by Hsap\CDKN1A^GMR.PH

(Schneiderman et al., 2010)

Suppressor of

Statement

Reference

Acf^EY08629/Scer\GAL4^ey.PH is a suppressor of abnormal eye color | dominant phenotype of bw^D

(Schneiderman et al., 2010)

Acf^EY08629/Scer\GAL4^GMR.PF is a suppressor of abnormal eye color | dominant phenotype of bw^D

(Schneiderman et al., 2010)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Acf^EY08629, Scer\GAL4^GMR.PF, bw^D has eye phenotype, non-enhanceable by Hsap\CDKN1A^GMR.PH

(Schneiderman et al., 2010)

NOT suppressed by

Statement

Reference

Acf^EY08629, Scer\GAL4^GMR.PF, bw^D has eye phenotype, non-suppressible by Hsap\CDKN1A^GMR.PH

(Schneiderman et al., 2010)

Suppressor of

Statement

Reference

Acf^EY08629/Scer\GAL4^ey.PH is a suppressor of eye phenotype of bw^D

(Schneiderman et al., 2010)

Acf^EY08629/Scer\GAL4^GMR.PF is a suppressor of eye phenotype of bw^D

(Schneiderman et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Mis-expression of Acf1^EY08629 driven by Scer\GAL4^GMR.PF restores eye pigmentation in bw^D/+ heterozygotes.

Mis-expression of Acf1^EY08629 driven by Scer\GAL4^ey.PH results in increased eye pigmentation in bw^D/+ heterozygotes compared with that in the parental bw^D/+ line.

(Schneiderman et al., 2010)

Xenogenetic Interactions

Statement

Reference

The increased eye pigmentation in bw^D/+ heterozygotes resulting from the mis-expression of Acf1^EY08629 driven by Scer\GAL4^GMR.PF is not affected by Hsap\CDKN1A^GMR.PH.

(Schneiderman et al., 2010)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

16432

y¹ w^67c23; P{EPgy2}Acf^EY08629

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Acf1^EY08629

Acf^EY08629

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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