FlyBase Allele Report: Dmel\spi[259]

General Information

Symbol

Dmel\spi²⁵⁹

Species

D. melanogaster

Name

FlyBase ID

FBal0154497

Feature type

allele

Associated gene

Dmel\spi

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

spi²⁵⁹/spi[+] is an enhancer of abnormal planar polarity phenotype of Scer\GAL4^hs.2sev, nmo^UAS.cUa

(Mirkovic et al., 2011)

spi²⁵⁹ is an enhancer of abnormal cell polarity phenotype of S^48-5

(Gaengel and Mlodzik, 2003)

NOT Enhancer of

Statement

Reference

spi²⁵⁹/spi[+] is a non-enhancer of visible phenotype of Scer\GAL4^Tub.PU, csw^N308D.UASp

(Oishi et al., 2006)

NOT Suppressor of

Statement

Reference

spi²⁵⁹/spi[+] is a non-suppressor of visible phenotype of Scer\GAL4^Tub.PU, csw^N308D.UASp

(Oishi et al., 2006)

Phenotype Manifest In

Enhancer of

Statement

Reference

spi²⁵⁹/spi[+] is an enhancer of ommatidium phenotype of Scer\GAL4^hs.2sev, nmo^UAS.cUa

(Mirkovic et al., 2011)

spi²⁵⁹ is an enhancer of ommatidium phenotype of S^48-5

(Gaengel and Mlodzik, 2003)

NOT Enhancer of

Statement

Reference

spi²⁵⁹/spi[+] is a non-enhancer of wing vein | ectopic phenotype of Scer\GAL4^Tub.PU, csw^N308D.UASp

(Oishi et al., 2006)

Suppressor of

Statement

Reference

spi²⁵⁹/spi[+] is a suppressor | partially of ommatidium phenotype of ec^spok

(Montrasio et al., 2007)

NOT Suppressor of

Statement

Reference

spi²⁵⁹/spi[+] is a non-suppressor of wing vein | ectopic phenotype of Scer\GAL4^Tub.PU, csw^N308D.UASp

(Oishi et al., 2006)

Additional Comments

Genetic Interactions

Statement

Reference

spi²⁵⁹/+ enhances the ommatidial over-rotation phenotype which is caused by expression of nmo^Scer\UAS.cUa under the control of Scer\GAL4^hs.2sev.

(Mirkovic et al., 2011)

The ommatidial rotation defects observed in ec^spok hemizygous adult eyes are partially suppressed by spi²⁵⁹/+.

(Montrasio et al., 2007)

S^48-5/spi²⁵⁹ mutants show 37.83%+-13.35 misrotated ommatidia compared to 9.55%+-1.43 seen in S^48-5 mutants alone.

(Gaengel and Mlodzik, 2003)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

spi-259

(Gaengel and Mlodzik, 2003)

spi²⁵⁹

(Mirkovic et al., 2011, Montrasio et al., 2007, Mirkovic and Mlodzik, 2006, Oishi et al., 2006)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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