FB2024_03 , released June 25, 2024
Allele: Dmel\crb11A2
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General Information
Symbol
Dmel\crb11A2
Species
D. melanogaster
Name
FlyBase ID
FBal0150531
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    crb11A2 mutant embryos display disorganised nervous systems, but the nervous system is not hyper-neuralised.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Suppressed by
    Statement
    Reference

    crb11A2 has epithelial cell phenotype, suppressible by scrib673

    Additional Comments
    Genetic Interactions
    Statement
    Reference

    The epithelial defects of crb11A2 embryos are markedly suppressed if the embryos are also mutant for scrib673; continuous patches of cuticle are formed in the double mutant embryos and the xonula adherens resembles that of wild-type embryos. The epidermis of late crb11A2 Df(3L)H99 embryos contains many multicellular highly polarised cyst-like structures.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    Name Synonyms
    Secondary FlyBase IDs
      References (4)