FlyBase Allele Report: Dmel\eff[D73]

General Information

Symbol

Dmel\eff^D73

Species

D. melanogaster

Name

FlyBase ID

FBal0147166

Feature type

allele

Associated gene

Dmel\eff

Associated Insertion(s)

Carried in Construct

Also Known As

ubcD1^D73

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy

(Kuo et al., 2006)

partially lethal (with eff^D112)

(Ryoo et al., 2002)

visible (with eff^D112)

(Ryoo et al., 2002)

Phenotype Manifest In

dendrite

(Kuo et al., 2006)

macrochaeta | ectopic (with eff^D112)

(Ryoo et al., 2002)

neuron

(Kuo et al., 2006)

Detailed Description

Statement

Reference

eff^D73 mutant C4da neuron clones exhibit defects in dendritic pruning. Mutants show similar dendritic morphology to wild-type clones at the onset of metamorphosis. However, at 18 hours after puparium formation, the mutant clones consistently retain intact, nonsevered larval dendrites.

(Kuo et al., 2006)

eff^D73/eff^D112 adults can survive at low penetrance. 21% of the survivors have extra macrochaetae on the scutellum.

(Ryoo et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

eff[+]/eff^D73 is an enhancer of visible phenotype of Dronc^pro.UAS, Scer\GAL4^GMR.PF

(Ryoo et al., 2002)

Suppressor of

Statement

Reference

eff[+]/eff^D73 is a suppressor of visible phenotype of hid^GMR.PG

(Ryoo et al., 2002)

eff[+]/eff^D73 is a suppressor of visible phenotype of rpr^GMR.PW

(Ryoo et al., 2002)

eff[+]/eff^D73 is a suppressor of visible phenotype of Diap1^RING.GMR

(Ryoo et al., 2002)

Phenotype Manifest In

Enhancer of

Statement

Reference

eff[+]/eff^D73 is an enhancer of pigment cell phenotype of Dronc^pro.UAS, Scer\GAL4^GMR.PF

(Ryoo et al., 2002)

Suppressor of

Statement

Reference

eff[+]/eff^D73 is a suppressor of eye phenotype of hid^GMR.PG

(Ryoo et al., 2002)

eff[+]/eff^D73 is a suppressor of eye phenotype of rpr^GMR.PW

(Ryoo et al., 2002)

eff[+]/eff^D73 is a suppressor of eye phenotype of Diap1^RING.GMR

(Ryoo et al., 2002)

eff[+]/eff^D73 is a suppressor of pigment cell phenotype of Diap1^RING.GMR

(Ryoo et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

The eye ablation phenotype of W^GMR.PG flies is partially suppressed by eff^D73/+. The eye ablation phenotype of rpr^GMR.PW flies is partially suppressed by eff^D73/+. The eye phenotype caused by expression of th^RING.GMR is suppressed by eff^D73/+ and more pigment cells survive.

(Ryoo et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

eff^D73

eff^Δ73

(Cenci et al., 2015)

ubcD1^D73

(Rumpf et al., 2014, Kuo et al., 2006, Ryoo et al., 2002)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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