FB2024_03 , released June 25, 2024
Allele: Dmel\DCTN2-p50UAS.cDa
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General Information
Symbol
Dmel\DCTN2-p50UAS.cDa
Species
D. melanogaster
Name
FlyBase ID
FBal0145073
Feature type
allele
Associated gene
Dmel\DCTN2-p50
Associated Insertion(s)
Carried in Construct
P{UAS-DCTN2-p50.D}
Also Known As
UAS-Dmn, UAS-Dynamitin, UAS-DCTN2-p50
Key Links
Transgenic product class
cDNA
(Duncan and Warrior, 2002)
wild_type
(Duncan and Warrior, 2002)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Duncan and Warrior, 2002)
wild_type
(Duncan and Warrior, 2002)
Mutagen
in vitro construct
(Duncan and Warrior, 2002)
Progenitor genotype
Carried in construct
P{UAS-DCTN2-p50.D}
Cytology
Description

Expression of full length DCTN2-p50 ORF (from cDNA LD07994 (Genome Systems) is under the control of UASt sequences.

(Duncan and Warrior, 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
DCTN2-p50
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of DCTN2-p50Scer\UAS.cDa under the control of Scer\GAL4btl.PU in embryos leads to defects in dorsal branch tube fusion.

      (Caviglia et al., 2016)

      DmnScer\UAS.cDa ; Scer\GAL4c355 flies lay eggs with normal dorsal appendages. DmnScer\UAS.cDa; Scer\GAL4elav-C155 flies have severe defects in axonal transport in the larval nervous system.

      (Duncan and Warrior, 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4GMR.long/DCTN2-p50UAS.cDa rescues DCTN2-p50k16109

      (Huang et al., 2015)
      Comments

      Expression of DCTN2-p50Scer\UAS.cDa driven by Scer\GAL4GMR.long rescues ERG phenotypes (reduced on/off transients in response to light) in DCTN2-p50k16109 homozygous mutant clones in the eye.

      (Huang et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      DCTN2-p50Scer\UAS.cDa
      DCTN2-p50UAS.cDa
      DmnScer\UAS.cDa
      dmnOE
      (Zheng et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (13)