FlyBase Allele Report: Dmel\Stat92E[UAS.cPa]

General Information

Symbol

Dmel\Stat92E^UAS.cPa

Species

D. melanogaster

Name

FlyBase ID

FBal0144532

Feature type

allele

Associated gene

Dmel\Stat92E

Associated Insertion(s)

Carried in Construct

P{UAS-Stat92E.P}

Also Known As

UAS-stat92E, UAS-stat

Key Links

Transgenic product class

wild_type

(Ghiglione et al., 2002)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Ghiglione et al., 2002)

Mutagen

in vitro construct

(Ghiglione et al., 2002)

Progenitor genotype

Carried in construct

P{UAS-Stat92E.P}

Cytology

Description

UAS regulatory sequences drive expression of Stat92E.

(Ghiglione et al., 2002)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Stat92E

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

border follicle cell, with Scer\GAL4^slbo.2.6

(Ghiglione et al., 2002)

Detailed Description

Statement

Reference

Stat92E^Scer\UAS.cPa driven by Scer\GAL4^nos.PU does not significantly affect germline stem cell number in testes.

(Tarayrah et al., 2015)

Ectopic expression of Stat92E^Scer\UAS.cPa in the eye disc from first instar larval stage under the control of Scer\GAL4^tub.PU (induced through heat-shock treatment of first instar larvae to inactivate Scer\GAL80^αTub84B.PL) significantly suppresses the increased apoptosis observed in cells of the first mitotic wave subjected to x-ray irradiation.

(Betz et al., 2008)

Expression of Stat92E^Scer\UAS.cPa under the control of Scer\GAL4^ey.PH, Scer\GAL4^elav.PLu, Scer\GAL4^GMR.PF or Scer\GAL4^dpp.blk1 does not result in any mutant eye phenotype.

(Bach et al., 2003)

Expression of Stat92E^Scer\UAS.cPa under the control of Scer\GAL4^slbo.2.6 results in aberrant migration of the border follicle cells.

(Ghiglione et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Stat92E^UAS.cPa, Scer\GAL4^nanos.PU is a suppressor | partially of decreased cell number | spermatogenesis | progressive phenotype of Rtel1^HMS00770, Scer\GAL4^nanos.PU

(Yang et al., 2021)

Stat92E^UAS.cPa, Scer\GAL4^nanos.PU is a suppressor of decreased cell number phenotype of Kdm5^GL00612, Scer\GAL4^nanos.PU

(Tarayrah et al., 2015)

Scer\GAL4^nanos.PU/Stat92E^UAS.cPa is a suppressor of decreased cell number | third instar larval stage phenotype of Df(2L)BSC184/Kdm5¹⁰⁴²⁴

(Tarayrah et al., 2015)

Scer\GAL4^nanos.PU/Stat92E^UAS.cPa is a suppressor of decreased occurrence of cell division | third instar larval stage phenotype of Df(2L)BSC184/Kdm5¹⁰⁴²⁴

(Tarayrah et al., 2015)

NOT Suppressor of

Statement

Reference

Scer\GAL4^ey.PH/Stat92E^UAS.cPa is a non-suppressor of visible phenotype of upd1^unspecified/Df(1)os1A2

(Bach et al., 2003)

Phenotype Manifest In

Suppressor of

Statement

Reference

Stat92E^UAS.cPa, Scer\GAL4^nanos.PU is a suppressor | partially of male germline stem cell | larval stage | decreased number phenotype of Rtel1^HMS00770, Scer\GAL4^nanos.PU

(Yang et al., 2021)

Stat92E^UAS.cPa, Scer\GAL4^nanos.PU is a suppressor of male germline stem cell phenotype of Kdm5^GL00612, Scer\GAL4^nanos.PU

(Tarayrah et al., 2015)

Scer\GAL4^nanos.PU/Stat92E^UAS.cPa is a suppressor of male germline stem cell | third instar larval stage phenotype of Df(2L)BSC184/Kdm5¹⁰⁴²⁴

(Tarayrah et al., 2015)

Stat92E^UAS.cPa, Scer\GAL4^slbo.2.6 is a suppressor of border follicle cell phenotype of Rac1^N17.UAS, Scer\GAL4^slbo.2.6

(Silver, 2005)

NOT Suppressor of

Statement

Reference

Scer\GAL4^ey.PH/Stat92E^UAS.cPa is a non-suppressor of eye phenotype of upd1^unspecified/Df(1)os1A2

(Bach et al., 2003)

Additional Comments

Genetic Interactions

Statement

Reference

Stat92E^Scer\UAS.cPa driven by Scer\GAL4^nos.PU suppresses the germline stem cell loss and premature differentiation (spermatogonial cysts next to the hub) seen in lid¹⁰⁴²⁴/Df(2L)BSC184 third instar larval testes.

Co-expression of Stat92E^Scer\UAS.cPa suppresses the germline stem cell loss seen in testes with lid^GL00612 driven by Scer\GAL4^nos.PU.

(Tarayrah et al., 2015)

Expression of Stat92E^Scer\UAS.cPa suppresses the border cell migration defect caused by expression of Rac1^N17.Scer\UAS under the control of Scer\GAL4^slbo.2.6.

(Silver, 2005)

Expression of Stat92E^Scer\UAS.cPa under the control of Scer\GAL4^ey.PH does not rescue the small eye phenotype of upd1^unspecified/Df(1)os1A2 flies.

(Bach et al., 2003)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^{VP16.mat.αTub67C}/Stat92E^UAS.cPa rescues Stat92E⁰⁶³⁴⁶

(Bertet et al., 2009)

Comments

Expression of Stat92E^Scer\UAS.cPa under the control of Scer\GAL4^{mat.αTub67C.T:Hsim\VP16} rescues the germ-band extension defects observed in Stat92E⁰⁶³⁴⁶ germ-line clones.

(Bertet et al., 2009)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Stat92E^Scer\UAS.cPa

Stat92E^UAS.cPa

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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