FB2024_03 , released June 25, 2024
Allele: Dmel\fruB.UAS.cUa
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General Information
Symbol
Dmel\fruB.UAS.cUa
Species
D. melanogaster
Name
FlyBase ID
FBal0144301
Feature type
allele
Associated gene
Dmel\fru
Associated Insertion(s)
Carried in Construct
P{UAS-fru.B.U}
Also Known As
UAS-fru-typeB+, UAS-fruB+
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Usui-Aoki et al., 2000)
Progenitor genotype
Carried in construct
P{UAS-fru.B.U}
Cytology
Description

UAS regulatory sequences drive expression of type B fru[+] cDNA, without the male-specific N terminal extension.

(Usui-Aoki et al., 2000)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
fru
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of fruB.Scer\UAS.cUa under the control of Scer\GAL4D42 in either wild-type or frusat females results in the formation of the muscle of Lawrence (MOL) in most of these flies (92% and 91% respectively). Some of these females have one to three MOLs in the A4 and A3 segment in addition to a pair of MOLs in the A5 segment.

      (Usui-Aoki et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      fruB.UAS.cUa/Scer\GAL4Toll-6-D42 partially rescues frusat

      (Usui-Aoki et al., 2000)
      Comments

      Expression of fruB.Scer\UAS.cUa under the control of Scer\GAL4D42 rescues the formation of the muscle of Lawrence in at least one side of the A5 segment in 80% of frusat homozygous males.

      (Usui-Aoki et al., 2000)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      fruB.Scer\UAS.cUa
      fruB.UAS.cUa
      Name Synonyms
      Secondary FlyBase IDs
        References (6)