FB2024_03 , released June 25, 2024
Allele: Dmel\Pvf2c06947
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General Information
Symbol
Dmel\Pvf2c06947
Species
D. melanogaster
Name
FlyBase ID
FBal0141574
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Vegf27Cbc6947
Key Links
Genomic Maps

Allele class
Nature of the Allele
Allele class
Progenitor genotype
Associated Insertion(s)
Cytology
Description

PBac{PB} insertion 5 nucleotides downstream of the 5' splice site of the fourth intron of Pvf2.

Allele components
Component
Use(s)
Mutations Mapped to the Genome
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

3 day old mutant flies show reduced BrdU incorporation in the adult midgut compared to controls, and the BrdU incorporation levels do not increase with age in the mutant flies. The mutant flies do not show a paraquat-induced increase in BrdU incorporation in the midgut cells, in contrast to what is seen in wild-type flies.

Pvf2c06947 mutants display a complete absence of hemocytes along the dorsal vessel, along with a reduction in hemocyte numbers migrating along the ventral midline.

No hemocyte migration defects are seen in mutants.

Mutant larvae show no obvious defects in blood cell counts.

External Data
Interactions
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Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
Reported As
Symbol Synonym
Pvf2c6947
Vegf27Cbc6947
Name Synonyms
Secondary FlyBase IDs
    References (7)