FB2024_03 , released June 25, 2024
Allele: Dmel\Notum2
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General Information
Symbol
Dmel\Notum2
Species
D. melanogaster
Name
FlyBase ID
FBal0138447
Feature type
allele
Associated gene
Dmel\Notum
Associated Insertion(s)
P{EPg}NotumEPg31259
Carried in Construct
Also Known As
EP-Notum
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Giraldez et al., 2002)
P-element activity
(Giraldez et al., 2002)
Progenitor genotype
NotumEPg31259
(Giraldez et al., 2002)
Associated Insertion(s)
P{EPg}NotumEPg31259
Cytology
Description

The P{EPg}NotumEPg31259 insertion is also still present on the chromosome.

(Giraldez et al., 2002)

Amino acid replacement: M146K.

(Giraldez et al., 2002)
Allele components
Component
Use(s)
Inserted element
P{EPg}
Regulatory region(s)
UASp
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3L:16,029,632..16,029,632 [+]
Nucleotide change:

T16029632A

Amino acid change:

M146K | Notum-PA

Reported amino acid change:

M146K

Comment:

The Notum2 mutation was induced on the NotumEPg31259 chromosome which carries a P{EPg} insertion approximately 1kb upstream of Notum. Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Giraldez et al., 2002)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Notum2
      Name Synonyms
      Secondary FlyBase IDs
        References (1)