FB2024_03 , released June 25, 2024
Allele: Dmel\gcmKG01117
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General Information
Symbol
Dmel\gcmKG01117
Species
D. melanogaster
Name
FlyBase ID
FBal0130283
Feature type
allele
Associated gene
Dmel\gcm
Associated Insertion(s)
P{SUPor-P}gcmKG01117
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{SUPor-P}gcmKG01117
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      gcmKG01117/gcm[+] is an enhancer of visible phenotype of DysRNAi.NH2.UAS, Scer\GAL4Act.PU

      (Kucherenko et al., 2008)

      gcmKG01117/gcm[+] is an enhancer of visible phenotype of DysRNAi.C.UAS, Scer\GAL4Tub.PU

      (Kucherenko et al., 2008)

      gcmKG01117/gcm[+] is an enhancer of visible phenotype of DgRNAi.UAS, Scer\GAL4Tub.PU

      (Kucherenko et al., 2008)
      Phenotype Manifest In
      Enhancer of
      NOT Enhancer of
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      gcm Dys double heterozygous flies (gcmKG01117/Df(3R)Exel6184) exhibit indirect flight muscle degeneration.

      gcmKG01117 DgO86 double heterozygous flies do not exhibit indirect flight muscle degeneration.

      One copy of gcmKG01117 does not enhance the indirect flight muscle degeneration seen when DysdsRNA.NH2.Scer\UAS is expressed under the control of Scer\GAL4Act.PU.

      One copy of gcmKG01117 does not enhance the indirect flight muscle degeneration seen when DgdsRNA.Scer\UAS is expressed under the control of Scer\GAL4tub.PU.

      gcmKG01117 Dg323 double heterozygous flies do not exhibit indirect flight muscle degeneration.

      (Kucherenko et al., 2011)

      One copy of gcmKG01117 strongly enhances the detached posterior crossvein phenotype seen when DysdsRNA.NH2.Scer\UAS is expressed under the control of Scer\GAL4Act.PU.

      One copy of gcmKG01117 moderately enhances the detached posterior crossvein phenotype seen when DysdsRNA.C.Scer\UAS is expressed under the control of Scer\GAL4tub.PU but produces extra wing vein material.

      One copy of gcmKG01117 enhances the posterior crossvein phenotype seen when DgdsRNA.Scer\UAS is expressed under the control of Scer\GAL4tub.PU.

      (Kucherenko et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      gcmKG01117
      (Kucherenko et al., 2011, Kucherenko et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)