FB2024_03 , released June 25, 2024
Allele: Dmel\dachsGC2
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General Information
Symbol
Dmel\dachsGC2
Species
D. melanogaster
Name
FlyBase ID
FBal0128006
Feature type
allele
Associated gene
Dmel\dachs
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
gamma ray
(Katz, 2001.12.11)
Progenitor genotype
Cytology
Description

Contains an inframe deletion, from N116 to P197 that removes part of the N-terminal extension of the d protein.

(Mao et al., 2006)

Deletion in a unique N-terminal pre-head domain that removes a leucine zipper.

(Katz, 2001.12.11)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2L:8,483,566..8,483,808 [+]
Comment:

Reportd as a in-frame deletion from N115 to A195.

(Mao et al., 2006)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The legs of dGC2 adults are short compared to wild type. Some dGC2 mutants have missing legs due to a leg disc eversion failure.

      The wings of dGC2 adults are small compared to wild type and exhibit abnormal wing patterning.

      (Mao et al., 2006)

      Weak hypomorph with respect to growth and segmentation, but results in a strong malformed leg phenotype.

      (Katz, 2001.12.11)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      dGC2
      (Mao et al., 2006)
      dachsGC2
      Name Synonyms
      Secondary FlyBase IDs
        References (2)