FB2024_03 , released June 25, 2024
Allele: Dmel\prosV3
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General Information
Symbol
Dmel\prosV3
Species
D. melanogaster
Name
FlyBase ID
FBal0125191
Feature type
allele
Associated gene
Dmel\pros
Associated Insertion(s)
P{GawB-Δ3.G}prosV3
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Grosjean et al., 2001)
Progenitor genotype
prosV1
(Grosjean et al., 2001)
Associated Insertion(s)
P{GawB-Δ3.G}prosV3
Cytology
Description

Imprecise excision of the P{GawB} element. Scer\GAL4 sequences are not present. w sequences are still present but the size of the w fragment is altered compared to prosV1. A 2.9kb BamHI-PstI fragment ("pBSK") from the 3' end of the element appears to be intact. Surrounding genomic sequences are unaffected.

(Grosjean et al., 2001)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The median lifespan for prosV3 animals (the age after egg laying at which 50% of homozygotes have died) is 10.34 days at 25oC.

      Homozygous second instar larvae show normal or nearly normal responses to 0.1M sucrose and to 0.3M NaCl in a taste response assay.

      (Grosjean et al., 2003)

      The courtship index of heterozygous males towards decapitated Canton-S males is significantly higher than that of wild-type males towards decapitated Canton-S males. The courtship index of heterozygous males towards decapitated Canton-S males is significantly lower than that of heterozygous prosV1 males towards decapitated Canton-S males. Homozygotes show high mortality during the first 2 days of adult life. Homozygous males are infertile, probably due to weakness.

      (Grosjean et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Voila3
      (Grosjean et al., 2001)
      prosV3
      (Grosjean et al., 2003)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)