FB2024_03 , released June 25, 2024
Allele: Dmel\tantUAS.cDa
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General Information
Symbol
Dmel\tantUAS.cDa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Dietrich
FlyBase ID
FBal0123678
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Progenitor genotype
Carried in construct
Cytology
Description

UASt regulatory sequences drive expression of a tant cDNA.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Ectopic tanScer\UAS.cDa expression, under the regulation of Scer\GAL4C96 along the wing margin, causes notching of the wing. Expression of tanScer\UAS.cDa under the regulation of Scer\GAL4h-1J3 often results in lethality at the pupal stage. The majority of the flies dissected from their pupal cases have legs with missing joints and only four tarsal segments. Duplication of the sex combs is frequently observed. Expression of tanScer\UAS.cDa under the regulation of Scer\GAL4h-1J3 results in the production of extra wing vein material in distal regions. Expression of tanScer\UAS.cDa under Scer\GAL4sca-537.4 control results in a dramatic loss of most bristles on the adult thorax. The majority of sensory cells on the notum are missing, suggesting that the bristle defects occur at the time of sensory organ precursor differentiation.

Expression of tanScer\UAS.cDa under the control of Scer\GAL4ptc-559.1 results in bristle defects. Escapers expressing tanScer\UAS.cDa under the control of Scer\GAL4h-1J3 at 18oC are weakly viable and have ectopic wing veins or vein material. Expression of tanScer\UAS.cDa under the control of Scer\GAL4C96 results in heavily notched wings.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
tanScer\UAS.cDa
tantScer\UAS.cDa
tantUAS.cDa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Dietrich
Secondary FlyBase IDs
    References (2)