FB2024_03 , released June 25, 2024
Allele: Dmel\nufEP3077
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General Information
Symbol
Dmel\nufEP3077
Species
D. melanogaster
Name
FlyBase ID
FBal0123255
Feature type
allele
Associated gene
Dmel\nuf
Associated Insertion(s)
P{EP}nufEP3077
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Bidet et al., 2003, Gene Disruption Project members, 2001-, Kraut et al., 2001)
Progenitor genotype
Associated Insertion(s)
P{EP}nufEP3077
Cytology
Description

P{EP} insertion in the 4th intron of nuf, upstream of the small isoform. The P{EP} element is oriented such that expression from the element should result in overexpression of nuf.

(Bidet et al., 2003)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      anterior fascicle & synapse, with Scer\GAL4elav-C155

      (Kraut et al., 2001)

      anterior fascicle & synapse | supernumerary, with Scer\GAL4elav-C155

      (Kraut et al., 2001)

      larval intersegmental nerve, with Scer\GAL4elav-C155

      (Kraut et al., 2001)
      Detailed Description
      Statement
      Reference

      Mutant larvae expressing nufEP3077 under the control of Scer\GAL4elav-C155 have ISN neuron pathfinding defects. Mutant larvae expressing nufEP3077 under the control of Scer\GAL4elav-C155 have excessive or ectopic synapses. Mutant larvae expressing nufEP3077 under the control of Scer\GAL4elav-C155 have reduced or abnormal synapses.

      (Kraut et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      EP3077EP3077
      nufEP3077
      Name Synonyms
      Secondary FlyBase IDs
        References (3)