DlScer\UAS.cLa third instar nota clones (under the regulation of Scer\GAL4mat.αTub67C.T:Hsim\VP16) usually contain two to four ectopic sensory organ precursors, with some clones appearing wild-type.
When DlScer\UAS.cLa is driven by Scer\GAL4GMR.PF, mutant adults have abnormal, rough eyes. However R8 organisation in the imaginal disc appears normal.
When DlScer\UAS.cLa is driven by Scer\GAL4h-1J3 the neural development in the eye disc begins normally in the posterior of the disc but becomes progressively disorganised more anteriorly as differentiation accelerates.
Scer\GAL4pros.PMG, DeltaUAS.cLa, neurUAS.cPa is a non-suppressor of abnormal neuroanatomy phenotype of spdoG104
DeltaUAS.cLa has sensory mother cell | third instar larval stage | ectopic phenotype, enhanceable by Scer\GAL4VP16.mat.αTub67C/fngUAS.cKa
DeltaUAS.cLa has sensory mother cell | third instar larval stage | ectopic phenotype, enhanceable by SerUAS.cGa/Scer\GAL4VP16.mat.αTub67C
DeltaUAS.cLa/Scer\GAL4GMR.PF is an enhancer of photoreceptor cell R8 phenotype of Nspl-1
Scer\GAL4twi.PG, DeltaUAS.cLa, neurUAS.cPa is a suppressor of embryonic pericardial cell phenotype of spdoG104
Scer\GAL4pros.PMG, DeltaUAS.cLa, neurUAS.cPa is a non-suppressor of dMP2 neuron | ectopic phenotype of spdoG104
Scer\GAL4pros.PMG, DeltaUAS.cLa, neurUAS.cPa is a non-suppressor of vMP2 neuron phenotype of spdoG104
Scer\GAL4pros.PMG, DeltaUAS.cLa, neurUAS.cPa is a non-suppressor of embryonic pericardial cell phenotype of spdoG104
Expression of neurScer\UAS.cPa and DlScer\UAS.cLa under the control of Scer\GAL4twi.PG has no effect on eve-positive pericardial cell numbers.
Expression of neurScer\UAS.cPa and DlScer\UAS.cLa under the control of Scer\GAL4twi.PG in a spdoG104 mutant background does not alter the number of eve-positive pericardial cells compared to spdoG104 mutant embryos.
Co-expression of neurScer\UAS.cPa and DlScer\UAS.cLa under the control of Scer\GAL4twi.PG in a spdoG104 mutant background partially restore svp-positive pericardial cell development by promoting more asymmetric divisions of progenitor cells.
DlScer\UAS.cLa, SerScer\UAS.cGa double-mutant third instar nota clones (under the regulation of Scer\GAL4mat.αTub67C.T:Hsim\VP16) typically contain ten or more ectopic sensory organ precursors. DlScer\UAS.cLa, fngScer\UAS.cKa double-mutant third instar nota clones (under the regulation of Scer\GAL4mat.αTub67C.T:Hsim\VP16) display a significantly higher number of sensory organ precursors per cluster than single mutants. Addition of the DlScer\UAS.cLa transgene, to DlRevF10 SerRX106 double mutant third instar nota clones, under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16, partially rescues the ectopic SOP phenotype, with approximately 8.5% of SOP positions exhibiting between four and eight SOPs.
When DlScer\UAS.cLa is driven by Scer\GAL4GMR.PF in a Nspl-1 background photoreceptor R8 differentiation is greatly reduced.