FB2024_03 , released June 25, 2024
Allele: Dmel\cherQ683X
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General Information
Symbol
Dmel\cherQ683X
Species
D. melanogaster
Name
FlyBase ID
FBal0121829
Feature type
allele
Associated gene
Dmel\cher
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Sokol and Cooley, 2001)
Progenitor genotype
Cytology
Description

Amino acid replacement: Q683term.

(Sokol and Cooley, 2003)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:17,107,504..17,107,504 [-]
Nucleotide change:

C17107504T

Reported nucleotide change:

C?T

Amino acid change:

Q683term | cher-PA; Q683term | cher-PG; Q713term | cher-PI; Q683term | cher-PL; Q713term | cher-PM; Q688term | cher-PN

Reported amino acid change:

Q683term

Comment:

The difference between the annotated and the reported site of the amino acid change is due to the use of a start codon 160aa further 5' in the annotated transcript relative to the published cDNA.

(Sokol and Cooley, 2003)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In cherQ683X homozygous adults, egg chamber formation is normal, but germline ring-canals are defective resulting in inviable, "dumpless" egg chambers.

      (Sokol and Cooley, 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Zucker

      (Sokol and Cooley, 2003)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      cherQ683X
      Name Synonyms
      Secondary FlyBase IDs
        References (2)