FB2024_03 , released June 25, 2024
Allele: Dmel\frayUAS.cLa
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General Information
Symbol
Dmel\frayUAS.cLa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Leiserson
FlyBase ID
FBal0121764
Feature type
allele
Associated gene
Dmel\fray
Associated Insertion(s)
Carried in Construct
P{PU4624}
Key Links
Transgenic product class
cDNA
(Leiserson et al., 2000)
wild_type
(Leiserson et al., 2000)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Leiserson et al., 2000)
wild_type
(Leiserson et al., 2000)
Mutagen
in vitro construct
(Leiserson et al., 2000)
Progenitor genotype
Carried in construct
P{PU4624}
Cytology
Description

UASt sequences drive expression of a 5kb imaginal disc cDNA of fray.

(Leiserson et al., 2000)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
fray
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      frayUAS.cLa/Scer\GAL4Gli-rL82.8 rescues frayr1

      (Leiserson et al., 2000)

      Scer\GAL4Ntan1-Mz317/frayUAS.cLa rescues frayr1

      (Leiserson et al., 2000)

      Scer\GAL4hs.PH/frayUAS.cLa rescues frayr1

      (Leiserson et al., 2000)

      frayUAS.cLa/Scer\GAL4Mz709 rescues frayr1

      (Leiserson et al., 2000)
      Partially rescues

      frayUAS.cLa partially rescues frayr1

      (Leiserson et al., 2000)
      Comments

      P{PU4624}61 insertion gives considerable rescue in the absence of a Scer\GAL4 driver. Driving expression of frayScer\UAS.cLa with a weak constitutive drive (P{hsGAL4.H}303-3) produces adults with visible defects such as reduced wings, eyes and legs. Lethality can be rescued by frayScer\UAS.cLa driven by Scer\GAL4Mz709 or Scer\GAL4Mz709.

      (Leiserson et al., 2000)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      frayScer\UAS.cLa
      frayUAS.cLa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Leiserson
      (Leiserson et al., 2000)
      Secondary FlyBase IDs
        References (1)