FB2024_03 , released June 25, 2024
Allele: Dmel\knrlUAS.cFa
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General Information
Symbol
Dmel\knrlUAS.cFa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Fuss
FlyBase ID
FBal0121712
Feature type
allele
Associated gene
Dmel\knrl
Associated Insertion(s)
Carried in Construct
P{UAS-knrl.F}
Key Links
Transgenic product class
cDNA
(Fuss et al., 2001)
wild_type
(Fuss et al., 2001)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Fuss et al., 2001)
wild_type
(Fuss et al., 2001)
Mutagen
in vitro construct
(Fuss et al., 2001)
Progenitor genotype
Carried in construct
P{UAS-knrl.F}
Cytology
Description

UAS sequences drive expression of an EcoRI fragment containing the coding region of the knrl cDNA.

(Fuss et al., 2001)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
knrl
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      knrlScer\UAS.cFa driven by Scer\GAL4fkh.14-3 leads to a mild reduction in the BrdU incorporation domain in the large intestine.

      (Fuss et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The combination of kniScer\UAS.cCa and knrlScer\UAS.cFa driven by Scer\GAL4fkh.14-3 has a strong effect on DNA replication in the hindgut. The BrDU is completely abolished. The large intestine region becomes reduced in size, although the cell number appears to be unaffected.

      (Fuss et al., 2001)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      knrlScer\UAS.cFa
      knrlUAS.cFa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Fuss
      (Fuss et al., 2001)
      Secondary FlyBase IDs
        References (1)