FB2024_03 , released June 25, 2024
Allele: Dmel\robo2EP
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General Information
Symbol
Dmel\robo2EP
Species
D. melanogaster
Name
FlyBase ID
FBal0120370
Feature type
allele
Associated gene
Dmel\robo2
Associated Insertion(s)
P{EP}robo2EP
Carried in Construct
Also Known As
EProbo2
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Bashaw et al., 2000)
Progenitor genotype
Associated Insertion(s)
P{EP}robo2EP
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of leaEP when driven by Scer\GAL4unspecified, causes a loss of commissure phenotype.

      (Bashaw et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhancer of
      Statement
      Reference

      Scer\GAL4ap-md544/robo2EP is a non-enhancer of abnormal neuroanatomy | embryonic stage phenotype of sli2

      (Evans and Bashaw, 2010)
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Scer\GAL4unspecified, robo2EP has symmetrical commissure phenotype, suppressible by enaGC1

      (Bashaw et al., 2000)
      NOT Enhancer of
      Statement
      Reference

      Scer\GAL4ap-md544/robo2EP is a non-enhancer of larval longitudinal connective phenotype of sli2

      (Evans and Bashaw, 2010)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      High levels of Scer\GAL4ap-md544>leaEP expression are insufficient to direct Scer\GAL4ap-md544-expressing axons away from the midline in a sli2 mutant genetic background.

      (Evans and Bashaw, 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      leaEP
      robo2EP
      (Bashaw et al., 2000)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)