FB2024_03 , released June 25, 2024
Allele: Dmel\slp1UAS.cSa
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General Information
Symbol
Dmel\slp1UAS.cSa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Struhl
FlyBase ID
FBal0120334
Feature type
allele
Associated gene
Dmel\slp1
Associated Insertion(s)
Carried in Construct
P{UAS(-FRT)slp1.S}
Also Known As
UAS-slp1
Key Links
Transgenic product class
wild_type
(Struhl, 2001.2.5)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Struhl, 2001.2.5)
Mutagen
FLPase
(Struhl, 2001.2.5)
Progenitor genotype
slp1FRT.Rnor\Cd2.UAS
(Struhl, 2001.2.5)
Carried in construct
P{UAS(-FRT)slp1.S}
Cytology
Description

FRT cassette has been excised, juxtaposing UAS regulatory sequences with slp1 coding sequences.

(Struhl, 2001.2.5)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
slp1
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In embryos expressing slp1Scer\UAS.cSa under the control of Scer\GAL4twi.PG LVM founder cell migration initiates similarly to the wild type, but the tracks become progressively irregular during germ band retraction at stage 12. By the end of germ band retraction none of the cells have reached the anterior of the trunk visceral mesoderm (TVM) compared to wild type.

      (Reim et al., 2012)

      When expression is driven by Scer\GAL4twi.PG and Scer\GAL4how-24B the trunk visceral mesoderm is strongly reduced.

      (Lee and Frasch, 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4twi.PG/slp1UAS.cSa is a non-suppressor of embryonic/larval somatic muscle & embryonic myoblast | dorsal phenotype of wgl-17

      (Lee and Frasch, 2000)

      Scer\GAL4twi.PG/slp1UAS.cSa is a non-suppressor of embryonic/larval dorsal vessel & embryonic myoblast phenotype of wgl-17

      (Lee and Frasch, 2000)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      G. Struhl

      (Lee and Frasch, 2000)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      slp1Scer\UAS.cSa
      slp1UAS.cSa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Struhl
      (Struhl, 2001.2.5)
      Secondary FlyBase IDs
        References (8)