FB2024_03 , released June 25, 2024
Allele: Dmel\Lim1UAS.cTa
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General Information
Symbol
Dmel\Lim1UAS.cTa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Tsuji
FlyBase ID
FBal0119467
Feature type
allele
Associated gene
Dmel\Lim1
Associated Insertion(s)
Carried in Construct
P{UAS-Lim1.T}
Also Known As
UAS-Lim1
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Tsuji et al., 2000)
Progenitor genotype
Carried in construct
P{UAS-Lim1.T}
Cytology
Description

UASt regulatory sequences drive expression of an EcoRI-XhoI fragment of Lim1 EST GH04929.

(Tsuji et al., 2000)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Lim1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mis-expression of Lim1Scer\UAS.cTa under the control of Scer\GAL4ey.PH reduces or abolishes the eye.

      Clones of cells mis-expressing Scer\GAL4αTub84B.PL>Lim1Scer\UAS.cTa in eye discs fail to differentiate as photoreceptors.

      (Roignant et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Lim1UAS.cTa/Scer\GAL4GH146 is a suppressor of abnormal neuroanatomy | somatic clone phenotype of ctC145

      (Komiyama and Luo, 2007)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The expression of Lim1Scer\UAS.cTa in clones of cells under the control of Scer\GAL4αTub84B.PL is unable to block photoreceptor differentiation when mis-expressed in Chi45F mutant cells.

      (Roignant et al., 2010)

      Lim1Scer\UAS.cTa; Scer\GAL4GH146 does not suppress the reduction in ventral antennal lobe projection neuron (vPN) numbers seen in ctC145/ctC145 somatic clones but does partially rescue the defects in targeting to antennal glomeruli seen in these neurons. Targeting defects in lateral antennal lobe projection neurons (lPN) in these clones are not rescued by Lim1Scer\UAS.cTa; Scer\GAL4GH146.

      (Komiyama and Luo, 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Lim1Scer\UAS.cTa
      Lim1UAS.cTa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Tsuji
      (Tsuji et al., 2000)
      Secondary FlyBase IDs
        References (5)