FB2024_03 , released June 25, 2024
Allele: Dmel\Cdk2UAS.Tag:MYC
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General Information
Symbol
Dmel\Cdk2UAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0119310
Feature type
allele
Associated gene
Dmel\Cdk2
Associated Insertion(s)
Carried in Construct
P{UAS-Cdk2-myc}
Also Known As
UAS-Cdk2-myc, UAS-Cdk2
Key Links
Transgenic product class
wild_type
(Meyer et al., 2000)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Meyer et al., 2000)
Mutagen
in vitro construct
(Meyer et al., 2000)
Progenitor genotype
Carried in construct
P{UAS-Cdk2-myc}
Cytology
Description

UASt sequences drive expression of Cdk2 tagged with six epitope copies of the Tag:MYC tag at the C terminus.

(Meyer et al., 2000)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Cdk2
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When driven by Scer\GAL4hs.2sev, Scer\GAL4GMR.PF or Scer\GAL4ey.PH, no eye phenotype is seen.

      (Datar et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of Cdk2Scer\UAS.T:Hsap\MYC with CycEScer\UAS.cLa driven by Scer\GAL4GMR.PF blocks some photoreceptor differentiation in the third instar eye disc. The phenotype of these discs is largely unaffected by upd1Scer\UAS.cCa.

      (Chen et al., 2003)

      When a combination of CycDScer\UAS.cDa and cdc2cScer\UAS.T:Hsap\MYC are driven by either, Scer\GAL4hs.2sev, Scer\GAL4GMR.PF or Scer\GAL4ey.PH no eye phenotype is seen.

      (Datar et al., 2000)
      Xenogenetic Interactions
      Statement
      Reference

      Expression of cdc2cScer\UAS.T:Hsap\MYC does not suppress the eye phenotypes seen when Mmus\Shisa5Scer\UAS.cGa is expressed under the control of Scer\GAL4ey.PH.

      (Gupta et al., 2008)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Cdk2Scer\UAS.T:Hsap\MYC
      Cdk2UAS.Tag:MYC
      cdc2cScer\UAS.T:Hsap\MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (12)