FB2024_03 , released June 25, 2024
Allele: Dmel\Dpunspecified
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General Information
Symbol
Dmel\Dpunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0118565
Feature type
allele
Associated gene
Dmel\Dp
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Dpunspecified transheterozygous larvae do not show significant changes in the size of salivary gland nuclei, as compared to controls.

        (Kim et al., 2018)

        Dpunspecified mutant eye discs display fewer apoptotic cells than wild-type controls after treatment with ionising irradiation.

        (Moon et al., 2008)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressor of
        Statement
        Reference

        Dpunspecified is a suppressor of increased cell death phenotype of Rbf120a

        (Moon et al., 2008)
        Phenotype Manifest In
        NOT Enhancer of
        Statement
        Reference

        Dpunspecified, Scer\GAL4GMR.PF is a non-enhancer of eye disc phenotype of Scer\GAL4GMR.PF, p53GUS.PB

        (Moon et al., 2008)

        Dpunspecified is a non-enhancer of phenotype of pngunspecified

        (Lee et al., 2001)
        Suppressor of
        Statement
        Reference

        Dpunspecified is a suppressor of eye disc phenotype of Rbf120a

        (Moon et al., 2008)
        NOT Suppressor of
        Statement
        Reference

        Dpunspecified, Scer\GAL4GMR.PF is a non-suppressor of eye disc phenotype of Scer\GAL4GMR.PF, p53GUS.PB

        (Moon et al., 2008)

        Dpunspecified is a non-suppressor of phenotype of pngunspecified

        (Lee et al., 2001)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The wave of apoptosis in Rbf120a mutant eye discs is completely suppressed by Dpunspecified.

        The apoptosis induced by the overexpression of p53GUS.PB via Scer\GAL4GMR.PFin the eye disc is unaffected by homozygous Dpunspecified.

        The elevated level of DNA-damage induced apoptosis in Rbf120a mutant eye discs is suppressed by Dpunspecified.

        (Moon et al., 2008)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        Dpunspecified is rescued by Dp+mMa

        (Myster et al., 2000)
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Dpunspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (4)