FB2024_03 , released June 25, 2024
Allele: Dmel\dlg1UAS.EGFP
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General Information
Symbol
Dmel\dlg1UAS.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0117554
Feature type
allele
Associated gene
Dmel\dlg1
Associated Insertion(s)
Carried in Construct
P{UAS-eGFP-dlg1-S48S}
Also Known As
UAS-Dlg-GFP, Dlg-GFP, UAS-eGFP-dlgA, UAS-Dlg:eGFP, UAS-EGFP::Dlg
Key Links
Transgenic product class
wild_type
(Koh et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Koh et al., 1999)
Mutagen
in vitro construct
(Koh et al., 1999)
Progenitor genotype
Carried in construct
P{UAS-eGFP-dlg1-S48S}
Cytology
Description

UASt regulatory sequences drive expression of the wild-type dlg1 coding region tagged at the 5' end with EGFP.

(Koh et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dlg1
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of dlg1Scer\UAS.T:Avic\GFP under the control of Scer\GAL4c747 does not significantly affect tolerance to ethanol vapor-induced sedation as compared to controls.

      (Maiya et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Phenotype Manifest In
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      the severity of wing defects observed upon the co-expression of HPV18\E6Scer\UAS.T:Hsap\MYC and Hsap\UBE3AScer\UAS.cRa under the control of Scer\GAL4ap.PU are not ameliorated by additional co-expression of dlg1Scer\UAS.T:Avic\GFP.

      (Padash Barmchi et al., 2016)
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4elav-C155/dlg1UAS.EGFP partially rescues dlg1S97-138

      (Mendoza-Topaz et al., 2008)
      Fails to rescue

      Scer\GAL4dlg1-intol/dlg1UAS.EGFP fails to rescue dlg1intol

      (Maiya et al., 2012)

      Scer\GAL4c747/dlg1UAS.EGFP fails to rescue dlg1intol

      (Maiya et al., 2012)

      Scer\GAL4elav-C155/dlg1UAS.EGFP fails to rescue dlg1S97-5

      (Mendoza-Topaz et al., 2008)
      Comments

      Expression of dlg1Scer\UAS.T:Avic\GFP under the control of Scer\GAL4dlg1-intol or Scer\GAL4c747 does not rescue the defective ethanol tolerance of dlg1intol/dlg1intol mutants.

      (Maiya et al., 2012)

      Phototaxis defects seen in dlg1S97-138 homozygotes are only partially rescued by expression of dlg1Scer\UAS.T:Avic\GFP under the control of Scer\GAL4elav-C155.

      Circadian locomotor behavior defects seen in dlg1S97-138 homozygotes are not rescued by expression of dlg1Scer\UAS.T:Avic\GFP under the control of Scer\GAL4elav-C155.

      Courtship behaviour defects seen in dlg1S97-5 homozygotes are not rescued by expression of dlg1Scer\UAS.T:Avic\GFP under the control of Scer\GAL4elav-C155.

      (Mendoza-Topaz et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      dlg1Scer\UAS.T:Avic\GFP
      dlg1UAS.EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (20)