Construct: Amino acid replacement: L1P. Amino acid replacement: Y12F. Amino acid replacement: I61L. Amino acid replacement: Q62R. Amino acid replacement: I64V. Amino acid replacement: L67I. Amino acids in the homeodomain and C terminus conserved region are changed to the equivalent residue in abd-A. The numbering is from the first amino acid in the homeodomain. Expression of this mutated Ubx1a is driven by Hsp70 promoter.
Ubiquitous expression of UbxB.hs transforms the three thoracic segments and the first abdominal segment into extra A2 segments.