Amino acid replacement: ?115term.
C7308815T
Q115term | brk-PA
?115term
Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.
In mutant larvae a denticle belt phenotype similar to that seen in brkF124 larvae is seen. In the developing nervous system of brkE427 mutant embryos, many of the late delaminating lateral and intermediate neuroblasts, but not the medial neuroblasts, are reduced in number. Neuroblast NB2-4 is often missing. NB3-3 and NB4-2 are missing in 18% and 27% of hemisegments respectively. NB1-1 and NB71- are unaffected. Some loss (14% missing) of NB6-4 and a strong loss of NB7-3 (75%) and NB7-4 (70%) is also seen. NB3-5 and NB5-6 are unaffected.