FB2024_03 , released June 25, 2024
Allele: Dmel\brkUAS.cLa
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General Information
Symbol
Dmel\brkUAS.cLa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Lammel
FlyBase ID
FBal0105063
Feature type
allele
Associated gene
Dmel\brk
Associated Insertion(s)
Carried in Construct
P{UAS-brk.L}
Also Known As
UAS-brk
Key Links
Transgenic product class
cDNA
(Lammel, 2000.5.19)
wild_type
(Lammel, 2000.5.19)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Lammel, 2000.5.19)
wild_type
(Lammel, 2000.5.19)
Mutagen
in vitro construct
(Lammel, 2000.5.19)
Progenitor genotype
Carried in construct
P{UAS-brk.L}
Cytology
Description

A full length brk cDNA fragment (NotI/KpnI) is driven by UAS sequences.

(Lammel, 2000.5.19)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
brk
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Most clones in the wing pouch expressing brkScer\UAS.cLa under the control of Scer\GAL4Act5C.PP are eliminated from the epithelium soon after clone induction in late first instar larvae.

      (Zirin and Mann, 2004)

      Clones in the eye disc expressing brkScer\UAS.cLa under the control of Scer\GAL4Act5C.PI prevent initiation of the morphogenetic furrow when they are at the posterior margin of the disc.

      (Baonza and Freeman, 2001)

      Ubiquitous expression of brkScer\UAS.cLa driven by Scer\GAL4da.G32 results in dorsal expansion of the salivary gland placodes but no extension along the anterior posterior axis.

      (Lammel et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Clones in the eye disc expressing both brkScer\UAS.cLa and DlScer\UAS.cJa under the control of Scer\GAL4Act5C.PI prevent furrow initialisation when they are at the posterior margin of the disc, as occurs in clones expressing brkScer\UAS.cLa alone under the control of Scer\GAL4Act5C.PI.

      (Baonza and Freeman, 2001)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      brkScer\UAS.cLa
      brkUAS.cLa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Lammel
      (Lammel et al., 2000)
      Secondary FlyBase IDs
        References (5)