FB2024_03 , released June 25, 2024
Allele: Dmel\shgdCPc3.UAS.sgGFP
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General Information
Symbol
Dmel\shgdCPc3.UAS.sgGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0103566
Feature type
allele
Associated gene
Dmel\shg
Associated Insertion(s)
Carried in Construct
P{UAS-dCPc3}
Key Links
Transgenic product class
inframe_deletion
(Oda and Tsukita, 1999)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Oda and Tsukita, 1999)
Mutagen
in vitro construct
(Oda and Tsukita, 1999)
Progenitor genotype
shgUAS.sgGFP
(Oda and Tsukita, 1999)
Carried in construct
P{UAS-dCPc3}
Cytology
Description

Amino acids 1367-1507 are deleted.

(Oda and Tsukita, 1999)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
shg
Tagged with
sgGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of shgdCPc3.Scer\UAS.T:Avic\GFP-rs when drive by Scer\GAL4neur-P72 does not perturb the orientation of the pI and pIIb divisions in the sensory organ lineage. However, the axis of the pIIa division is altered. In wild-type this cell divides in the same orientation as its mother. 38% of pIIa cells divide at an α angle of more than 20o (compared to 2% for wild-type). Also in 60% of the dividing pIIa cells the mitotic spindle does not line up with the anterior accumulation of shgdCPc3.Scer\UAS.T:Avic\GFP-rs.

      (Le Borgne et al., 2002)

      When transiently transformed with Scer\GAL4Act5C.PHb into S2 cells, promoted a strong cell aggregation phenotype.

      (Oda and Tsukita, 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      shgdCPc3.UAS.sgGFP/Scer\GAL4btl.PS fails to rescue Df(2R)E2/shg2

      (Oda and Tsukita, 1999)
      Comments

      The addition of shgdCPc3.Scer\UAS.T:Avic\GFP-rs, driven by Scer\GAL4btl.PS, into shg2/Df(2R)E2 flies fails to rescue their tracheal fusion phenotype.

      (Oda and Tsukita, 1999)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Carried in a plasmid and co transfected with Scer\GAL4Act5C.PHb into S2 cells.

      (Oda and Tsukita, 1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      shgdCPc3.Scer\UAS.T:Avic\GFP-rs
      shgdCPc3.UAS.rsGFP
      shgdCPc3.UAS.sgGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (3)