UASt regulatory sequences drive expression of Rel tagged at the N-terminal end with Tag:polyHis.
Expression of RelScer\UAS.T:Zzzz\His6 under the control of Scer\GAL4repo has no significant effect on the number of apoptotic cells in the adult brain.
Flies expressing RelScer\UAS.T:Zzzz\His6 via Scer\GAL4Cg.PA show lower levels of viral replication 5 days after intrathoracic infection with 200 pfu of Sindbis virus compared to controls.
Expression of RelScer\UAS.T:Zzzz\His6 under the control of Scer\GAL4cad-md509 increases BrdU incorporation in the large and small cells in the adult posterior midgut, indicating an increase in cellular proliferation.
RelUAS.Tag:polyHis/Scer\GAL4Cg.PA partially rescues RelE20
RelUAS.Tag:polyHis/Scer\GAL4c564 partially rescues RelE20
RelUAS.Tag:polyHis/Scer\GAL4cad-em459 partially rescues RelE20
Expressing RelUAS.Tag:polyHis under the control of Scer\GAL4Cg.PA fully rescues lipid storage defects and only partially rescues the reduced resistance to starvation in RelE20/RelE20 adults.
Expression of RelScer\UAS.T:Zzzz\His6 in the intestine, driven by Scer\GAL4cad-em459, results in the increased survival rate of RelE20 flies to control levels following infection with the ROS-resistant KNU53775 yeast strain. However, expression of RelScer\UAS.T:Zzzz\His6 in the fat body, driven by Scer\GAL4c564, does not increase the survival rates of RelE20 flies following KNU53775 infection. In contrast, expression of RelScer\UAS.T:Zzzz\His6 increases survival rates of RelE20 flies in response to infection with Erwinia carotovora carotovora 15 when driven by Scer\GAL4c564 but does not increase survival when driven with Scer\GAL4cad-em459.
Rescues the immune defects of RelE20 flies when expressed under the control of Scer\GAL4hs.PB.