FB2024_03 , released June 25, 2024
Allele: Dmel\kek1k07332
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General Information
Symbol
Dmel\kek1k07332
Species
D. melanogaster
Name
FlyBase ID
FBal0101796
Feature type
allele
Associated gene
Dmel\kek1
Associated Insertion(s)
P{lacW}kek1k07332
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Spradling, 1999.12.9, Spradling et al., 1999)
Progenitor genotype
Associated Insertion(s)
P{lacW}kek1k07332
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      kek1k07332 mutant germline clones show oogenesis arrest and oocyte mislocalisation.

      (Kucherenko et al., 2008)

      No obvious phenotype.

      (Spradling et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      kek1[+]/kek1k07332 is an enhancer of visible phenotype of DgRNAi.UAS, Scer\GAL4Tub.PU

      (Kucherenko et al., 2008)
      Suppressor of
      Statement
      Reference

      kek1[+]/kek1k07332 is a suppressor of visible phenotype of DysRNAi.C.UAS, Scer\GAL4Tub.PU

      (Kucherenko et al., 2008)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      kek1[+]/kek1k07332 is an enhancer of posterior crossvein phenotype of DgRNAi.UAS, Scer\GAL4Tub.PU

      (Kucherenko et al., 2008)
      Suppressor of
      Statement
      Reference

      kek1[+]/kek1k07332 is a suppressor of posterior crossvein phenotype of DysRNAi.C.UAS, Scer\GAL4Tub.PU

      (Kucherenko et al., 2008)
      Other
      Statement
      Reference

      DysRNAi.C.UAS, kek1[+]/kek1k07332 has wing vein | ectopic phenotype

      (Kucherenko et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      One copy of kek1k07332 moderately suppresses the detached posterior crossvein phenotype seen when DysdsRNA.C.Scer\UAS is expressed under the control of Scer\GAL4tub.PU but produces extra wing vein material.

      One copy of kek1k07332 enhances the posterior crossvein phenotype seen when DgdsRNA.Scer\UAS is expressed under the control of Scer\GAL4tub.PU.

      (Kucherenko et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      Separable from: l(2)k07332k07332. The lethality of the "l(2)k07332" chromosome (caused by l(2)k07332k07332) is separable from the P{lacW}kek1k07332 insertion.

      (Spradling, 1999.12.9)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      BEST:GM02380k07332
      kek1k07332
      n(2)k07332
      (Spradling, 1999.12.9, Spradling et al., 1999)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)