FB2024_03 , released June 25, 2024
Allele: Dmel\B-H1UAS.cSa
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General Information
Symbol
Dmel\B-H1UAS.cSa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Sato
FlyBase ID
FBal0097411
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-BarH1M13, UAS-BarH1
Key Links
Nature of the Allele
Progenitor genotype
Carried in construct
Cytology
Description

Expression of B-H1 2.1kb cDNA is governed by UAS regulatory sequences.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

When B-H1Scer\UAS.cSa is driven by Scer\GAL4lz-gal4 in the eye disc, furrow migration is blocked and photoreceptor differentiation is eliminated.

Expression of B-H1Scer\UAS.cSa under the control of Scer\GAL4ey.PB results in deletion of the eye.

Expression of B-H1Scer\UAS.cSa under the control of Scer\GAL4dpp.blk1 blocks furrow formation in the eye disc.

Overexpression of B-H1Scer\UAS.cSa under the control of Scer\GAL4dpp.blk1 results in ectopic fold formation in the leg disc along the boundary of B-H1 expressing and non-expressing cells. The formation of the endogenous central fold is interrupted. No ectopic folding is seen prior to the onset of central folding. Overexpression of B-H1Scer\UAS.cSa under the control of Scer\GAL4ap-md544 occasionally results in the partial transformation of tarsal segment 4 into tarsal segment 5; the ventralmost bristle at the distal tip of segment 4 is transformed from a thick, black bristle (characteristic of segment 4) into a thin and less-pigmented bristle (characteristic of segment 5). Tarsal segments 4 and 5 are partially fused with each other.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Scer\GAL4B-H1.B4.5.B-H2.S8-driven expression of B-H1Scer\UAS.cSa rescues the microchaetae phenotype but not the PS macrochaetae phenotype of Df(1)BH2.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
B-H1Scer\UAS.cSa
B-H1UAS.cSa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Sato
Secondary FlyBase IDs
    References (15)