FB2024_03 , released June 25, 2024
Allele: Dmel\proshs.PM
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General Information
Symbol
Dmel\proshs.PM
Species
D. melanogaster
Name
heat shock construct of Matsuzaki
FlyBase ID
FBal0096723
Feature type
allele
Associated gene
Dmel\pros
Associated Insertion(s)
Carried in Construct
P{hs-pros.24H2}
Also Known As
hs-pros
Key Links
Transgenic product class
wild_type
(Manning and Doe, 1999)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Manning and Doe, 1999)
Mutagen
in vitro construct
(Manning and Doe, 1999, Reddy and Rodrigues, 1999)
Progenitor genotype
Carried in construct
P{hs-pros.24H2}
Cytology
Description

An Hsp70 promoter drives expression of pros.

(Manning and Doe, 1999)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
pros
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      scutum & external sensory organ

      (Reddy and Rodrigues, 1999)

      scutum & microchaeta

      (Manning and Doe, 1999)

      scutum & microchaeta & tormogen cell

      (Manning and Doe, 1999)

      scutum & microchaeta & trichogen cell

      (Manning and Doe, 1999)
      Detailed Description
      Statement
      Reference

      Animals expressing proshs.PM using heat shock for 1 hour at 14 hours after puparium formation show fairly severe balding in the notum; 90% of the flies lack approximately 20% of the microchaetae. Double bristles are seen at the edge of the bald areas, and very rarely, triple bristles are seen.

      (Manning and Doe, 1999)

      Flies expressing proshs.PM between 15-20 hours after puparium formation using heat shock show partial balding of the notum.

      (Reddy and Rodrigues, 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Other
      Statement
      Reference

      proshs.PM, svp1.hs has antenna phenotype

      (Sen et al., 2003)

      proshs.PM, svp1.hs has microchaeta & antennal segment 3 phenotype

      (Sen et al., 2003)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      When proshs.PM and svp1.hs are co-expressed after heat shocking mutant pupae at 32oC for 6 hours starting at 10 hours APF, a reduction in external structures on the adult antenna is seen. No alteration in the numbers of glia or neurons is seen.

      (Sen et al., 2003)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      proshs.PM
      Name Synonyms
      heat shock construct of Matsuzaki
      (Manning and Doe, 1999)
      Secondary FlyBase IDs
        References (3)