FB2024_03 , released June 25, 2024
Allele: Ecol\lacZbrk-X47
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General Information
Symbol
Ecol\lacZbrk-X47
Species
E. coli
Name
FlyBase ID
FBal0095771
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
P{PZ}X47
Carried in Construct
Also Known As
brk-lacZ, brkX47-lacZ
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Campbell and Tomlinson, 1999)
Progenitor genotype
P{PZ}AP-2α06694
(Campbell and Tomlinson, 1999)
Associated Insertion(s)
P{PZ}X47
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      wing disc | posterior
      (Campbell and Tomlinson, 1999)
      wing disc | anterior
      (Campbell and Tomlinson, 1999)
      inner proliferation zone | restricted
      (Apitz and Salecker, 2015)
      wandering third instar larval stage
      wing disc | lateral | restricted
      (Cook et al., 2004)
      Additional Information
      Statement
      Reference

      EcollacZbrk-X47 is expressed in dpp-negative cells positioned in the inner proliferation zone of the larval optic anlage.

      (Apitz and Salecker, 2015)

      EcollacZbrk-X47 is expressed in the wing disc from the anterior edge to several cell diameters anterior to the outer edge or presumptive wing vein L2, and from presumptive wing vein L5 to the posterior edge of the disc.. brk expression is complementary to that of bi.

      (Cook et al., 2004)

      Enhancer trap expression is observed at the anterior and posterior extremes of the wing disc. It is also detected in a gradient along the anterior-posterior axis in the wing pouch. In dpp mutants, expression is ubiquitous in the disc.

      (Campbell and Tomlinson, 1999)
       
      Marker for
      Reflects expression of
      brk
      (Apitz and Salecker, 2015, Cook et al., 2004, Campbell and Tomlinson, 1999)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ecol\lacZbrk-X47
      brkX-47
      (Torres-Vazquez et al., 2000)
      brkx47
      (Pinto-Teixeira et al., 2018)
      Name Synonyms
      Secondary FlyBase IDs
        References (18)