FB2024_03 , released June 25, 2024
Allele: Dmel\Rap1hs.PA
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General Information
Symbol
Dmel\Rap1hs.PA
Species
D. melanogaster
Name
heat shock construct of Asha
FlyBase ID
FBal0095628
Feature type
allele
Associated gene
Dmel\Rap1
Associated Insertion(s)
Carried in Construct
P{hs-Rap1.A}
Key Links
Transgenic product class
cDNA
(Asha et al., 1999)
wild_type
(Asha et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Asha et al., 1999)
wild_type
(Asha et al., 1999)
Mutagen
in vitro construct
(Asha et al., 1999)
Progenitor genotype
Carried in construct
P{hs-Rap1.A}
Cytology
Description

Expression of a Rap1 cDNA is driven by a heat shock promoter.

(Asha et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
Rap1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Rap1hs.PA partially rescues Rap1rvB1/Df(3L)R-E

      (Asha et al., 1999)
      Comments

      Daily 30 minute heat shocks from day 3 to day 7 of development rescue the larval lethality of RrvB1/Df(3L)R-E. Flies are morphologically wild type - except under minimal heat shock conditions when eyes are roughened. Rescued flies can survive without further heat shock for weeks though show a higher mortality than their wild type siblings. Rescued females stop laying eggs within a day or two of heat shock cessation.

      (Asha et al., 1999)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Rhs.PA
      Rap1hs.PA
      Name Synonyms
      heat shock construct of Asha
      (Asha et al., 1999)
      Secondary FlyBase IDs
        References (1)