The expression of Su(H)Scer\UAS.T:Hsap\MYC,T:Hsim\VP16 under the control of Scer\GAL4lz-gal4 leads to significant increases in both the number and size of third instar larval circulating crystal cells, as compared to controls.
Stage 13 embryos expressing Su(H)Scer\UAS.T:Hsap\MYC,T:Hsim\VP16 under the control of Scer\GAL4sim.P3.7 have approximately 16 anterior midline glia (AMG) compared to six in wild type. By stage 16 the number of AMG has reduced to 7, compared to three in wild type.
When Su(H)Scer\UAS.T:Hsap\MYC,T:Hsim\VP16 is driven by Scer\GAL4how-24B in the mesoderm differentiation of the visceral mesoderm is disrupted.
When expression is driven by Scer\GAL4dpp.blk1 adult wings show ectopic margin structures, similar to those induced by 'intra' forms of N.
Su(H)VP16.UAS.Tag:MYC/Scer\GAL4repo-M1B is a suppressor of abnormal neuroanatomy | recessive phenotype of Nl1N-ts1
Scer\GAL415J2/Su(H)VP16.UAS.Tag:MYC is a non-suppressor of abnormal neuroanatomy | recessive phenotype of Nl1N-ts1
Su(H)VP16.UAS.Tag:MYC/Scer\GAL4repo-M1B is a suppressor of pioneer neuron phenotype of Nl1N-ts1
Scer\GAL415J2/Su(H)VP16.UAS.Tag:MYC is a non-suppressor of pioneer neuron phenotype of Nl1N-ts1
Expression of Su(H)Scer\UAS.T:Hsap\MYC,T:Hsim\VP16 in glia under the control of Scer\GAL4repo-M1B suppresses the Nl1N-ts1 longitudinal pioneer axon phenotype.
Expression of Su(H)Scer\UAS.T:Hsap\MYC,T:Hsim\VP16 in the pioneer neurons under the control of Scer\GAL415J2 fails to suppress the Nl1N-ts1 longitudinal pioneer axon phenotype.